Position Summary:

TScan Therapeutics is a clinical-stage biotech seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are looking for a highly motivated researcher to join our team as an Associate Scientist, , with focus on Next Generation Sequencing, to oversee the operations of the NGS lab and current NGS team. The ideal candidate should have relevant experience in molecular biology, Next Generation Sequencing library preparation, demonstrated experience in people management, and enjoy fast-paced, collaborative, and vibrant culture. A team player with a sense of urgency will thrive in this role.

Responsibilities:

• Oversee the operations of the NGS lab and build a variety of NGS libraries (ex. single-cell seq based on 10x Genomics platform, Amplicon-seq libraries for a variety of in-house experiments, RNA-seq libraries from tumor samples and cell lines, immune repertoire libraries from primary samples)
• Manage, support, and develop existing NGS team of individual contributors, ensuring objectives are aligned with the team and company goals
• Work closely with team members and scientists in other groups to provide NGS insights when designing experiments and processing samples
• Optimize and troubleshoot workflows and develop new technologies and lab capabilities (NGS workflows, automation, novel assays, etc.)
• Operate in-house Illumina and Nanopore sequencers and automation hardware (QIAcube, Bravo)
• Analyze data, communicate results with co-workers, and present work regularly

Requirements:

• Master’s degree with 5-7+ years of relevant laboratory experience, Bachelor’s degree with 8+ years of relevant laboratory experience
• Hands-on experience with NGS library preparation
• Experience with molecular biology techniques, such as PCR, DNA purification and quantification methods
• Prior experience in a people management role, with proven ability to train and develop a group of researchers
• Experience with cell culture and immunology a plus
• Excellent written and verbal communication skills, attention to detail, and ability to document experiments in an organized and timely fashion
• Ability to work efficiently both independently and in a collaborative team environment
• Ability to quickly pivot and adapt with any changing priorities
• Strong reasoning and analytical skills

About TScan:

TScan Therapeutics is a fully integrated, next-generation TCR-T cell therapy company. Founded in 2018, TScan’s platform was developed by Stephen Elledge, Ph.D., and Tomasz Kula, Ph.D., at Brigham and Women’s Hospital and Harvard Medical School. TScan’s transformative platform enables rapid discovery of TCRs and targets for engineered T cell therapy. This technology is extremely versatile and is applicable across multiple therapeutic areas beyond cancers, including autoimmune disorders and infectious diseases.

Do YOU have the anatomy of a TScanner?

Our talented, compassionate, and intelligent team is what makes TScan a Top Place to Work (as ranked by The Boston Globe). Our state-of-the-art offices with over 70,000 square feet of premium lab space, including an internal GMP manufacturing suite, are an environment that supports innovation, camaraderie, and professionalism. We are passionate, fun, flexible, and team oriented. Sound like you? Apply today.

EEO Statement

TScan is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. TScan provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with TScan regarding a reasonable accommodation in connection with the hiring process and/or to perform the responsibilities of the position for which the applicant has applied, please contact the recruiter.

Recruitment & Staffing Agencies

TScan Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to TScan Therapeutics or its employees is strictly prohibited unless contacted directly by TScan Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of TScan Therapeutics, and TScan Therapeutics will not owe any referral or other fees with respect thereto.