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Engineering
Immunity

TScan is a fully integrated clinical-stage biotechnology company focused on developing a robust pipeline of T cell receptor-engineered T cell (TCR-T) therapies for the treatment of patients with cancer.

Cell attacking cancer to show TCR-T cancer therapies
Portrait of a joyful woman laughing to show hope for TCR-T cancer therapies.
Scientist using an automated pipette system to analyze laboratory samples for website for TCR-T cancer therapies

Building toward

patient impact

TScan is advancing engineered T cell therapy candidates from discovery to clinical development, with a primary focus on in vivo engineering of TCR-Ts to treat solid tumors. Our programs are designed to translate deep scientific insight into first-in-class therapies with the potential to address unmet medical needs for patients.

Latest Press Releases

2019

First novel target discovered using proprietary screening platform

2021

Target for solid tumor (head + neck cancer) discovered; TScan goes public; GMP facility opened; first two INDs filed

2023

First patient dosed with TSC-101 in Phase 1 ALLOHA trial; partnership with Amgen initiated; initial positive data from ALLOHA

2025

Continued positive data from Phase 1 ALLOHA trial supports development of registrational study in AML and MDS; preclinical development of in vivo engineering platform for solid tumors initiated

2018

TScan founded; first employees hired

2020

First clinical hematology candidate discovered; manufacturing technology developed to genetically engineer T cells

2022

IND for multiplex therapy in solid tumors cleared by FDA

2024

$200M raised; RMAT designation received for TSC-101; continued positive data from Phase 1 ALLOHA